Respiratory Trend Report

Week ending August 24th, 2025

HealthTrackRx
Trend Update

As students head back to school this month, this mid-summer update of 2025 respiratory trends reviews activity over the past several weeks (June 29-August 24, 2025) and highlights how major respiratory viruses are circulating compared to typical seasonal patterns.

Respiratory Trend Report

Week ending August 24th, 2025

Get Updates

HealthTrackRx
Trend Update

As students head back to school this month, this mid-summer update of 2025 respiratory trends reviews activity over the past several weeks (June 29-August 24, 2025) and highlights how major respiratory viruses are circulating compared to typical seasonal patterns.

Infection Trends

COVID-19 positivity has been climbing steadily, rising from 4.1% in late June to 10.0% by mid-August, signaling active summer circulation.
Rhinovirus/Enterovirus continues to dominate, more than doubling from 18.7% to 38.7% positivity, and is currently the leading driver of respiratory illness.
Enterovirus D68 has shown a gradual increase from 0.2% to 2.8%, indicating we can expect to see circulation of this virus again this fall.
Parainfluenza virus peaked earlier this summer and is now declining, dropping from 7.8% to 3.4% positivity.

Infection Trends

COVID-19 positivity has been climbing steadily, rising from 4.1% in late June to 10.0% by mid-August, signaling active summer circulation.
Rhinovirus/Enterovirus continues to dominate, more than doubling from 18.7% to 38.7% positivity, and is currently the leading driver of respiratory illness.
Enterovirus D68 has shown a gradual increase from 0.2% to 2.8%, indicating we can expect to see circulation of this virus again this fall.
Parainfluenza virus peaked earlier this summer and is now declining, dropping from 7.8% to 3.4% positivity.

Seasonal Outlook

COVID-19 is expected to continue circulating through late summer and early fall, though whether this trend persists into winter remains uncertain.
Rhinovirus/Enterovirus levels are likely to remain high as schools reopen, driving early fall respiratory illness.
Enterovirus D68 may continue to rise into September. In the last several years, EVD68 transmission has been sporadic, often circulating in the population in alternating respiratory seasons. Rising positivity suggests that spread of this virus may begin to be a consistent contributor to early respiratory season spread.

Parainfluenza and Human metapneumovirus are likely to stay at low levels until late fall or early spring, when their next seasonal cycles usually begin.
RSV typically reemerges in the fall; current low levels suggest circulation could begin ramping up within the next 1–2 months.
Influenza virus is expected to remain minimal until winter onset, with the possibility of early regional circulation later in the fall.

Seasonal Outlook

COVID-19 is expected to continue circulating through late summer and early fall, though whether this trend persists into winter remains uncertain.
Rhinovirus/Enterovirus levels are likely to remain high as schools reopen, driving early fall respiratory illness.
Enterovirus D68 may continue to rise into September. In the last several years, EVD68 transmission has been sporadic, often circulating in the population in alternating respiratory seasons. Rising positivity suggests that spread of this virus may begin to be a consistent contributor to early respiratory season spread.
Parainfluenza and Human metapneumovirus are likely to stay at low levels until late fall or early spring, when their next seasonal cycles usually begin.
RSV typically reemerges in the fall; current low levels suggest circulation could begin ramping up within the next 1–2 months.
Influenza virus is expected to remain minimal until winter onset, with the possibility of early regional circulation later in the fall.

Trending Up

COVID-19 Coronavirus (SARS-CoV-2)
Enterovirus D68
Rhinovirus/Enterovirus

Trending Down

Adenovirus
Parainfluenza virus (types 1, 2, 3, and 4)
Human metapneumovirus

Remaining Level

Respiratory syncytial virus (RSV)
Influenza virus A, B
Coronavirus (229E, NL63, OC43, and HKU1)

Trending Up

COVID-19 Coronavirus (SARS-CoV-2)
Enterovirus D68
Rhinovirus/Enterovirus

Trending Down

Adenovirus
Parainfluenza virus (types 1, 2, 3, and 4)
Human metapneumovirus

Remaining Level

Respiratory syncytial virus (RSV)
Influenza virus A, B
Coronavirus (229E, NL63, OC43, and HKU1)

7-Day Positivity Rate – COVID-19 Coronavirus (SARS-CoV-2)

This report reflects observed trends in HealthTrackRx testing positivity data, does not convey medical advice, and is provided for informational purposes only. Individuals experiencing respiratory symptoms should consult with their healthcare provider.

Download Respiratory Trend Reports [PDF]

8-25-2025 PDF