Respiratory Trend Report

Week ending February 21st, 2026

HealthTrackRx
Trend Update

Respiratory virus activity remains elevated nationally, with several pathogens continuing to circulate at moderate to high levels. Over the past two weeks, overall activity has remained largely stable, with the exception of increasing human metapneumovirus activity.

Respiratory Trend Report

Week ending February 21st, 2026

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HealthTrackRx
Trend Update

Respiratory virus activity remains elevated nationally, with several pathogens continuing to circulate at moderate to high levels. Over the past two weeks, overall activity has remained largely stable, with the exception of increasing human metapneumovirus activity.

Infection Trends

  • Influenza A/B: Remains elevated at 13.4%, consistent with peak winter activity. Positivity appears to be stabilizing over the past two weeks.

  • Seasonal Coronaviruses (229E, NL63, HKU1, and OC43): Activity remains elevated at 12.3%, with plateauing positivity following prior upward trends.

  • Rhinovirus/Enterovirus: Continues to be the most frequently detected pathogen at 14.3%, with stable to slightly declining positivity over recent weeks.

  • Respiratory Syncytial Virus (RSV): Positivity remains stable around 7%, with no significant directional change over the past two weeks.

  • Human Metapneumovirus (hMPV): Demonstrating a continued upward trend, increasing to 4.4%, representing the most notable growth among circulating pathogens.

  • Adenovirus, Parainfluenza Viruses (Types 1–4), COVID-19 (SARS-CoV-2), Enterovirus D68: All remain stable at low levels (<2%).

Infection Trends

  • Influenza A/B: Remains elevated at 13.4%, consistent with peak winter activity. Positivity appears to be stabilizing over the past two weeks.

  • Seasonal Coronaviruses (229E, NL63, HKU1, and OC43): Activity remains elevated at 12.3%, with plateauing positivity following prior upward trends.

  • Rhinovirus/Enterovirus: Continues to be the most frequently detected pathogen at 14.3%, with stable to slightly declining positivity over recent weeks.

  • Respiratory Syncytial Virus (RSV): Positivity remains stable around 7%, with no significant directional change over the past two weeks.

  • Human Metapneumovirus (hMPV): Demonstrating a continued upward trend, increasing to 4.4%, representing the most notable growth among circulating pathogens.

  • Adenovirus, Parainfluenza Viruses (Types 1–4), COVID-19 (SARS-CoV-2), Enterovirus D68: All remain stable at low levels (<2%).

Seasonal Outlook

  • Influenza A/B is expected to gradually decline through late winter.
  • RSV activity is likely to plateau before trending downward.
  • Human metapneumovirus is expected to continue increasing into early spring.

  • Seasonal coronaviruses may begin to taper in the coming weeks.

  • Rhinovirus/Enterovirus will likely persist at baseline levels with potential spring increases.

Seasonal Outlook

  • Influenza A/B is expected to gradually decline through late winter.
  • RSV activity is likely to plateau before trending downward.
  • Human metapneumovirus is expected to continue increasing into early spring.

  • Seasonal coronaviruses may begin to taper in the coming weeks.

  • Rhinovirus/Enterovirus will likely persist at baseline levels with potential spring increases.

Trending Up

  • Human Metapneumovirus

Trending Down

  • None

Remaining Level

  • Influenza A/B
  • Seasonal Coronavirus (229E, NL63, OC43, HKU1)
  • Rhinovirus/Enterovirus

  • Respiratory Syncytial Virus (RSV)

  • COVID-19 Coronavirus (SARS-CoV-2)

  • Adenovirus

  • Parainfluenza Virus (Types 1–4)
  • Enterovirus D68

Trending Up

  • Human Metapneumovirus

Trending Down

  • None

Remaining Level

  • Influenza A/B
  • Seasonal Coronavirus (229E, NL63, OC43, HKU1)
  • Rhinovirus/Enterovirus

  • Respiratory Syncytial Virus (RSV)

  • COVID-19 Coronavirus (SARS-CoV-2)

  • Adenovirus

  • Parainfluenza Virus (Types 1–4)
  • Enterovirus D68

7 Day Influenza Virus A/B Map

This report reflects observed trends in HealthTrackRx testing positivity data, does not convey medical advice, and is provided for informational purposes only. Individuals experiencing respiratory symptoms should consult with their healthcare provider.

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HealthTrackRx Respiratory Resource Library
HealthTrackRx Respiratory Resource Library

A collection of whitepapers, articles and webinars from our scientists.