Respiratory Trend Report

Week ending December 28th, 2025

HealthTrackRx
Trend Update

Respiratory season continues to progress with several increases in positivity rates seen in various respiratory illnesses across the nation. Providers should consider taking time to discuss hygiene best practices and contact precautions with sick individuals. The slight decrease in positivity rates across respiratory illnesses may be attributable to reduced testing volume during the holiday season (December 15–28) and may not reflect an actual decrease in infections.

Respiratory Trend Report

Week ending December 28th, 2025

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HealthTrackRx
Trend Update

Respiratory season continues to progress with several increases in positivity rates seen in various respiratory illnesses across the nation. Providers should consider taking time to discuss hygiene best practices and contact precautions with sick individuals. The slight decrease in positivity rates across respiratory illnesses may be attributable to reduced testing volume during the holiday season (December 15–28) and may not reflect an actual decrease in infections.

Infection Trends

Influenza A/B had a positivity increase from 16.3% to 20.8% by the end of December 21st.
Respiratory Syncytial Virus (RSV)’s positivity rate increased from 5.4% to 6.2% by December 28.
Human Metapneumovirus positivity increased from 2.1% to 2.8% by December 28.
COVID-19 prevalence has been steadily inclining, from 1.7% to 1.8% by December 21.

Infection Trends

Influenza A/B had a positivity increase from 16.3% to 20.8% by the end of December 21st.
Respiratory Syncytial Virus (RSV)’s positivity rate increased from 5.4% to 6.2% by December 28.
Human Metapneumovirus positivity increased from 2.1% to 2.8% by December 28.
COVID-19 prevalence has been steadily inclining, from 1.7% to 1.8% by December 21.

Seasonal Outlook

RSV and Influenza are beginning their expected seasonal climb, with Influenza sharply increasing as the US enters its winter season.
Rhinovirus/Enterovirus is trending downward, but still contributes to the highest positivity rate overall.
COVID-19 remains low and steady, with no major shifts noted.
Coronaviruses (229E, NL63, HKU1, OC43) positivity trajectory is similar to Influenza A/B, making it worthwhile to continue monitoring throughout this winter season.

Seasonal Outlook

RSV and Influenza are beginning their expected seasonal climb, with Influenza sharply increasing as the US enters its winter season.
Rhinovirus/Enterovirus is trending downward, but still contributes to the highest positivity rate overall.
COVID-19 remains low and steady, with no major shifts noted.
Coronaviruses (229E, NL63, HKU1, OC43) positivity trajectory is similar to Influenza A/B, making it worthwhile to continue monitoring throughout this winter season.

Trending Up

Respiratory syncytial virus (RSV)
Influenza A/B
Human Metapneumovirus
Enterovirus D68
Coronaviruses (229E, NL63, HKU1, OC43)

Trending Down

Adenovirus
COVID-19 Coronavirus (SARS-CoV-2)
Rhinovirus/Enterovirus
Parainfluenza Viruses (types 1-4)

Remaining Level

Trending Up

Respiratory syncytial virus (RSV)
Influenza A/B
Human Metapneumovirus
Enterovirus D68
Coronaviruses (229E, NL63, HKU1, OC43)

Trending Down

Adenovirus
COVID-19 Coronavirus (SARS-CoV-2)
Rhinovirus/Enterovirus
Parainfluenza Viruses (types 1-4)

Remaining Level

7 Day Influenza Virus A/B Map

This report reflects observed trends in HealthTrackRx testing positivity data, does not convey medical advice, and is provided for informational purposes only. Individuals experiencing respiratory symptoms should consult with their healthcare provider.