Respiratory Trend Report

Week ending October 12th, 2025

HealthTrackRx
Trend Update

Rhinovirus/Enterovirus remains the most common respiratory virus circulating nationwide, though its activity has dipped slightly over the past two weeks, now representing 33% of positive results. As we move further into the respiratory season, other viruses are beginning to rise. Parainfluenza infections continue to climb, while Adenovirus activity has seen a modest uptick as well. RSV is starting to gain traction, reaching 1.3% nationally, with notably higher levels in Florida. COVID-19 rates have eased following summer peaks, and Enterovirus D68 has held steady around 3%. Influenza activity remains low overall but is beginning to climb, with higher positivity rates seen in several states including Florida, Pennsylvania, Texas, Wisconsin, and Wyoming.

Respiratory Trend Report

Week ending October 12th, 2025

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HealthTrackRx
Trend Update

Rhinovirus/Enterovirus remains the most common respiratory virus circulating nationwide, though its activity has dipped slightly over the past two weeks, now representing 33% of positive results. As we move further into the respiratory season, other viruses are beginning to rise. Parainfluenza infections continue to climb, while Adenovirus activity has seen a modest uptick as well. RSV is starting to gain traction, reaching 1.3% nationally with notably higher levels in Florida. COVID-19 rates have eased following summer peaks, and Enterovirus D68 has held steady around 3%. Influenza activity remains low overall but is beginning to climb, with higher positivity rates seen in several states including Florida, Pennsylvania, Texas, Wisconsin, and Wyoming.

Infection Trends

Rhinovirus/Enterovirus: Remains dominant, but decreased to 33%.
Parainfluenza (types 1–4): Increased from 7% to 8.5%, continuing to rise early in the respiratory season.
Adenovirus: Slight increase from previous weeks from 2.1% to 2.7%.
Respiratory Syncytial Virus (RSV): Increase to 1.30%, with levels reaching as high as 6.0% last week in Florida.
COVID-19 (SARS-CoV-2): Declined from 3.6% to 3.0%, consistent with tapering circulation after summer peaks.
Enterovirus D68: Minimal increase from 2.9% to 3.0%, remaining steady over the last two weeks.
Influenza A & B: Increase to 0.9%, with higher positivity rates noted in Florida, Pennsylvania, Texas, Wisconsin, and Wyoming.

Infection Trends

Rhinovirus/Enterovirus: Remains dominant, but decreased to 33%.
Parainfluenza (types 1–4): Increased from 7% to 8.5%, continuing to rise early in the respiratory season.
Adenovirus: Slight increase from previous weeks from 2.1% to 2.7%.
Respiratory Syncytial Virus (RSV): Increase to 1.30%, with levels reaching as high as 6.0% last week in Florida.
COVID-19 (SARS-CoV-2): Declined from 3.6% to 3.0%, consistent with tapering circulation after summer peaks.
Enterovirus D68: Minimal increase from 2.9% to 3.0%, remaining steady over the last two weeks.
Influenza A & B: Increase to 0.9%, with higher positivity rates noted in Florida, Pennsylvania, Texas, Wisconsin, and Wyoming.

Seasonal Outlook

Rhinovirus/Enterovirus is expected to remain a major driver of respiratory illness through October but is not expected to significantly climb as RSV and Influenza begin to more widely circulate and dominate the respiratory landscape.
Parainfluenza virus is showing modest growth and may contribute more substantially to early fall cases.
COVID-19 continues to wane, but should be monitored closely for potential shifts with seasonal changes.
RSV and Influenza are continuing to climb with higher positivity rates already noted in certain states.

Seasonal Outlook

Rhinovirus/Enterovirus is expected to remain a major driver of respiratory illness through October but is not expected to significantly climb as RSV and Influenza begin to more widely circulate and dominate the respiratory landscape.
Parainfluenza virus is showing modest growth and may contribute more substantially to early fall cases.
COVID-19 continues to wane, but should be monitored closely for potential shifts with seasonal changes.
RSV and Influenza are continuing to climb with higher positivity rates already noted in certain states.

Trending Up

Parainfluenza virus (types 1, 2, 3, and 4)
Adenovirus
Respiratory syncytial virus (RSV)
Influenza virus A, B

Trending Down

Rhinovirus/ Enterovirus
COVID-19 Coronavirus (SARS-CoV-2)

Remaining Level

Coronavirus (229E, NL63, OC43, and HKU1)
Human metapneumovirus
Enterovirus D68

Trending Up

Parainfluenza virus (types 1, 2, 3, and 4)
Adenovirus
Respiratory syncytial virus (RSV)
Influenza virus A, B

Trending Down

Rhinovirus/ Enterovirus
COVID-19 Coronavirus (SARS-CoV-2)

Remaining Level

Coronavirus (229E, NL63, OC43, and HKU1)
Human metapneumovirus
Enterovirus D68

7-Day Positivity Rate Respiratory (Influenza A,B)

This report reflects observed trends in HealthTrackRx testing positivity data, does not convey medical advice, and is provided for informational purposes only. Individuals experiencing respiratory symptoms should consult with their healthcare provider.

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