Respiratory Trend Report

Week ending November 30th, 2025

HealthTrackRx
Trend Update

Respiratory virus activity over the last two weeks shows notable early-season increases in RSV and influenza, a continued decline in rhinovirus/enterovirus, and overall stable to slightly rising levels of other respiratory pathogens. RSV and influenza are now showing their first meaningful seasonal upticks, while COVID-19 remains low but steady. Most other respiratory viruses remain near baseline.

Respiratory Trend Report

Week ending November 30th, 2025

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HealthTrackRx
Trend Update

Respiratory virus activity over the last two weeks shows notable early-season increases in RSV and influenza, a continued decline in rhinovirus/enterovirus, and overall stable to slightly rising levels of other respiratory pathogens. RSV and influenza are now showing their first meaningful seasonal upticks, while COVID-19 remains low but steady. Most other respiratory viruses remain near baseline.

Infection Trends

Rhinovirus/Enterovirus continues to drive the largest share of positives but declined from 30.6% to 26.2% over the last 2 weeks, marking a gradual downward trend after fall peaks.
Respiratory Syncytial Virus (RSV) increased from 2.8% to 4.0%, continuing a steady seasonal rise consistent with early winter surges.
Influenza A/B shows a significant week-over-week increase from 2.7% to 5.0% over the last 2 weeks, indicating early influenza activity beginning to take hold. The highest activity was observed in Texas with 13.0% positivity in the last 7 days, followed by Delaware at 9.5%, and Alabama, Florida, and Wisconsin all at 9.1%.
Parainfluenza (types 1–4) decreased slightly from 8.1% to 6.7% but remains elevated compared to baseline fall patterns.

Infection Trends

Rhinovirus/Enterovirus continues to drive the largest share of positives but declined from 30.6% to 26.2% over the last 2 weeks, marking a gradual downward trend after fall peaks.
Respiratory Syncytial Virus (RSV) increased from 2.8% to 4.0%, continuing a steady seasonal rise consistent with early winter surges.
Influenza A/B shows a significant week-over-week increase from 2.7% to 5.0% over the last 2 weeks, indicating early influenza activity beginning to take hold. The highest activity was observed in Texas with 13.0% positivity in the last 7 days, followed by Delaware at 9.5%, and Alabama, Florida, and Wisconsin all at 9.1%.
Parainfluenza (types 1–4) decreased slightly from 8.1% to 6.7% but remains elevated compared to baseline fall patterns.

Seasonal Outlook

RSV and Influenza are beginning their expected seasonal climb and may increase sharply as winter approaches.
Rhinovirus/Enterovirus is trending downward but still contributes the highest positivity rate overall.
COVID-19 remains low and steady, with no major shifts noted.
Parainfluenza remains elevated for late fall but has started to decline.
Other pathogens, including adenovirus, human metapneumovirus, and seasonal coronaviruses, are circulating at low to moderate baseline levels.

Seasonal Outlook

RSV and Influenza are beginning their expected seasonal climb and may increase sharply as winter approaches.
Rhinovirus/Enterovirus is trending downward but still contributes the highest positivity rate overall.
COVID-19 remains low and steady, with no major shifts noted.
Parainfluenza remains elevated for late fall but has started to decline.
Other pathogens, including adenovirus, human metapneumovirus, and seasonal coronaviruses, are circulating at low to moderate baseline levels.

Trending Up

Influenza A/B
Respiratory syncytial virus (RSV)
Coronaviruses (229E, NL63, HKU1, OC43)
Human Metapneumovirus

Trending Down

Rhinovirus/Enterovirus
Parainfluenza virus (types 1–4)

Remaining Level

Adenovirus
COVID-19 Coronavirus (SARS-CoV-2)
Enterovirus D68

Trending Up

Influenza A/B
Respiratory syncytial virus (RSV)
Coronaviruses (229E, NL63, HKU1, OC43)
Human Metapneumovirus

Trending Down

Rhinovirus/Enterovirus
Parainfluenza virus (types 1–4)

Remaining Level

Adenovirus
COVID-19 Coronavirus (SARS-CoV-2)
Enterovirus D68

7 Day Influenza Virus A/B Map

This report reflects observed trends in HealthTrackRx testing positivity data, does not convey medical advice, and is provided for informational purposes only. Individuals experiencing respiratory symptoms should consult with their healthcare provider.